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yeaB [2018-06-29 15:04:01]
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yeaB [2018-06-29 15:04:01]

secondary manganese (II) efflux pump
Locus
BSU06320
Isoelectric point
5.63
Molecular weight
31.63 kDa
Protein length
290 aa Sequence Blast
Gene length
870 bp Sequence Blast
Function
Mn(II) export
Product
manganese (II) efflux pump
Essential
no
Synonyms
ydxT,yeaB
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Transporters → Transporters/ other → Other exporters
  • Cellular processes → Transporters → Transporters/ other → Metal ion exporters
  • Cellular processes → Homeostasis → Trace metal homeostasis (Cu, Zn, Ni, Mn, Mo) → Manganese
  • Groups of genes → Membrane proteins

    • Gene

    Coordinates
    686,962 → 687,834

    The protein

    Catalyzed reaction/ biological activity

  • efflux of Mn(II) PubMed

    • Protein family

  • cation diffusion facilitator (CDF) family PubMed

    • Paralogous protein(s)

  • YdbO, MneP

    • Structure

  • 5VRF ()28% identity

    • Localization

  • cell membrane (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    mneS
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • MntR: transcription activation, PubMed, in MntR regulon
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    Biological materials

    Mutant

  • MGNA-A914 (yeaB::erm), available at the NBRP B. subtilis, Japan
  • BKE06320 (ΔmneS::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATACAAAACCTCCTCTCGC, downstream forward: _UP4_TAATGGAGCTTCCTGTCACA
  • BKK06320 (ΔmneS::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATACAAAACCTCCTCTCGC, downstream forward: _UP4_TAATGGAGCTTCCTGTCACA

    • References

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